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The WTX News Teams works around the clock to deliver, breaking news and news Briefings to you on a daily basis. It is our opinion that sometimes you need information, not speculation so we try to cut through the bull**** and give you that in your Daily News Briefing.

Metro – Treasons to be cheerful Summary of the front page Metro leads on the apparent attempted Wagner coup in Russia which occurred over the weekend. Alongside a headline punning a famous Ian Dury and the Blockheads song, the paper reports that Kyiv is “reaping the benefits” of the chaos caused by the mercenary mutiny. Plenty of fun in the Glastonbury sun was had over the weekend and the paper carries a colourful montage of some of the acts who smashed the festival – including Rick Astley and Guns N’ Roses. Today’s top stories Like this article? Leave a comment…

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Financial Times – Aborted Wagner insurrection lays bare cracks in Putin’s authority Summary of the front page The aborted coup in Russia over the weekend is the lead story in the Financial Times with the paper saying the attempted insurrection “lays bare the cracks in Putin’s authority”. The paper also says a growing number of fearful Tory MPs with slim majorities are cutting back on the time spent in Westminster in a bid to shore up their prospects in their constituencies. Today’s top stories Like this article? Leave a comment UK National newspapers

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The Guardian – Wagner uprising reveals cracks in Putin’s authority, says US Summary of the front page The Wagner Group uprising over the weekend is the lead story in The Guardian. The paper cites US sources claiming that the mercenary mutiny has revealed “cracks in Putin’s authority”. Yevgeny Prigozhin is pictured shaking hands after his deal which will see him move to Belarus. The front page also carries a huge review of the Glastonbury Festival. Today’s top stories Like this article? Leave a comment UK National newspapers

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The Sun – Fergie: I’ve got cancer Summary of the front page Sarah Ferguson’s breast cancer scare is the lead story on the front of The Sun, with the paper reporting that the duchess was diagnosed during a routine mammogram. The paper quotes a friend who says Sarah Ferguson is very grateful to the staff at the King Edward VII Hospital who carried out the surgery and looked after her. The tabloid also says Simon Cowell’s home had a raid foiled by… The Sun. Today’s top stories Like this article? Leave a comment UK National newspapers

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Daily Mirror – Fergie: My breast cancer op Summary of the front page The Duchess of York’s breast cancer diagnosis makes the splash on the front of the Daily Mirror, with the paper reporting the royal has left the hospital following her operation. The paper reports her family is “rallying” around her and that she had no symptoms – it was caught during a routine check-up. The front page reports on Sir Elton John as it declares his classic Glastonbury set list as a “belter”. Today’s top stories Like this article? Leave a comment UK National newspapers

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Daily Express – Duchess breast cancer operation is success Summary of the front page The Daily Express leads on the news that the Duchess of York has undergone a successful operation to treat breast cancer after the disease was spotted during a routine screening. The front page also reports Sir Elton John’s spectacular final show closing Glastonbury and it also queries how long President Vladimir Putin has left in power. Today’s top stories Like this article? Leave a comment UK National newspapers

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Met police name new suspect in Stephen Lawrence murder The Guardian says The Metropolitan police have named a major new suspect in the Stephen Lawrence murder, admitting too many mistakes were made in the initial investigation. Matthew White, who died in 2021 aged 50, was named after a BBC investigation into the killing of the black teenager, who was murdered in a racist attack in south-east London in April 1993. The BBC reported that five prime suspects became widely known after the murder, but the public inquiry said there were “five or six” attackers. In 2011, White was named publicly…

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Met ‘reviewing’ fresh information into racist murder of Stephen Lawrence as new suspect is named LBC says Scotland Yard is “reviewing” fresh information into the racist murder of Stephen Lawrence after a new suspect was named. Mr Lawrence was stabbed to death in Eltham, south-east London, on April 22, 1993. A sixth suspect has now been named as Matthew White, who died in August 2021. White first came to police attention as a witness in the same year – he told officers he had visited the home address of two other suspects on the night of Stephen’s murder. He was…

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Greek Conservatives win second election and pledge more reforms  Kyriakos Mitsotakis, the Greek conservative leader, has beaten his centre-left rival in the second election in a month. He has said he has a “strong mandate” to move faster on the path of change. Mitsotakis’ New Democracy party (ND) won 40.5% of the national vote – that’s almost 23 points ahead of Alexis Tsipras’s Syriza party. Although Mitsotakis beat Syriza in May, he had called for new elections in a bid to secure a majority. “ND is today the most powerful centre-right party in Europe,” he told supporters in Athens. Kyriakos…

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Today’s news summary – Paper Talk Monday’s front pages report on several stories including the news of Sarah, the Duchess of York’s cancer diagnosis. She has had surgery and is recovering at Windsor. The unrest in Russia dominates many of the papers, as well as Sir Elton John’s Glastonurry performance – his last ever UK gig, as he prepares to retire from touring.  Sarah Ferguson’s breast cancer  Most papers report on the Duchess of York, with many papers leaving space on their front pages for it. The Daily Express says the operation was a success and she was discharged over…

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Sergei Shoigu visiting the advanced control post of Russian troops at an unknown location (Picture: Reuters)

Russia’s defence minister came out of hiding for the first time today since the rebellion from the Wagner Group mercenaries.

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Different cancer types behave in different ways (Picture: Getty/Science Photo Libra)

Scientists have identified how a specific substance plays a key role in helping prostate cancer to spread and become harder to treat.

They hope the findings might offer new treatment options for aggressive prostate cancer.

A team at Nottingham Trent University found that ‘transglutaminase 2’ (TG2), which is abundant in many of the body’s cells, is responsible for driving a process which leads to the progression and spreading of the disease.

In the UK, prostate cancer is the most common cancer in men – with more than 52,000 diagnosed every year.

Early prostate cancer cells require the male hormone androgen to grow.

However they can become androgen-independent and therefore harder to treat with current therapies, as they advance.

Researchers suggest that until now it has not been clear how that process occurs.

‘This finding has opened a significant pathway for understanding other key mechanisms prostate cancer cells utilise to evade key regulatory pathways,’ Dr Adeola Atobatele, a scientist on the study.

The new study found that a mutant form of TG2 is overproduced in prostate cancer and remains trapped inside the nucleus of cells.

There it restricts the levels of androgen response – making cancer cells the more aggressive androgen-independent.

It also increases expression of the protein mucin-1, which is known to be responsible for the growth and spreading of cancer.

Mucin-1 forms a mucous barrier on cell surfaces which protects cancer cells, researchers found.

When researchers analysed biopsies of prostate cancer, they identified increased levels of TG2.

Based on the findings, the team proposes that controlling the activity of TG2 and mucin-1 may offer a new therapeutic option for aggressive prostate cancer.

Lead scientist Dr Elisabetta Verderio Edwards, from Nottingham Trent University’s School of Science and Technology, said: ‘We wanted to explore why some cancer cells become androgen-independent and as a result more aggressive and harder to treat.

‘Transglutaminase is a multifunctional protein in all tissues and is involved in multiple processes.

‘We have now deepened our understanding of its key role in aggressive disease in prostate cancer patients.

‘Understanding this pathway is incredibly important.

‘This process plays a key role in cancer’s ability to evade treatment and so warrants further investigation in terms of potential future treatment and therapy.’

The latest study, which also involved the Polyclinic Hospital University (University of Messina) in Italy, is published in the journal Cell Death and Disease.

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